子宫动脉栓塞治疗子宫肌瘤的生命质量观察

目的 探讨子宫动脉栓塞前后子宫肌瘤患者的生命质量变化.方法 对2003年1月-2005年3月我院收治118例行子宫动脉栓塞术患者,应用子宫肌瘤症状和生命质量(UFS-QOL)调查表评价其术前及术后生命质量的变化,并对患者进行满意度调查.同时观察子宫及肌瘤大小变化.结果 术后6个月肌瘤及子宫体积平均分别缩小49.6%和45.2%.栓塞术后患者临床症状明显好转,生命质量各因子评分均较术前明显提高,差异均有统计学意义(P＜0.001),65%患者临床症状明显改善,接近80%患者肯定或很可能再次选择UAE治疗子宫肌瘤.结论 行UAE治疗子宫肌瘤,可明显提高患者的生命质量,有较高的满意度.

Evaluation of life quality after arterial uterine embolization for leiomyoma

Objective To evaluate the quality of life in women with uterine leiomyoma after treatment by uterine arterial embolization.Methodes 118 patients of uterine leiomyoma were treated by uterine arterial embolization(UAE) from January 2003 to March 2005.The quality of life was measured by a fibroid specific symptom and HRQOL questionnaire pre-and post-embolization.Patients' satisfaction was surveyed together with decrease of fibroids'mass measurement.Results The decrease of fibroid size and uterine volume were 49.6% and 45.2% at 6 months after embolization with simultaneously obvious improvement of clinical symptoms.The scores of quality of life obviously improved in all follow-up subscales(P < 0.001).No amenorrhea occurred during the period of observation with more than 60% of respondents acknowledging the positive improvement in fibroid-related symptoms though UAE;and 80% would probably or definitely take UAE as the first choice of treatment again.Conclusion The treatment of symptomatic leiomyomas by UAE can improve the quality of life dramatically with a promising satisfaction.(J Intervent Radiol,2007,16:240-242)