四种调理脾胃药对大鼠胃肠激素影响的差异性研究

目的:探讨四种经典的调理脾胃方药对大鼠胃肠激素的影响。方法:SD大鼠,分别胃饲补中益气汤、大承气汤、归牌汤、温胆汤、双蒸水,用药15天后,放免法测大鼠小肠、血液中SS、SP、VIP、NPY的含量。结果:补中益气汤可显著升高小肠及血液SS的含量;大承气汤可显著升高小肠SS、降低小肠SP、降低小肠和血液VIP的含量;归脾汤可显著升高血液SS、降低小肠和血液SP、降低小肠VIP的含量。

Study on Difference of Effects of Four Kinds of Spleen and Stomach Regulating Medicines on GastrointestinalHormones

To study the effect of four Treatment Recipe Durg To Spleen - stomach On Peptide Neurotrans-mitters. Method: Mice were separately administeredr with Buzhongyiqitang, Dachengqitang, Guipitang and Wendantang 15 days. Then check - up the content of SS,SP,VIP,NPY in the blood and by adioimmunoassay. Results: To peripheral peptide, Buzhongyiqitang can increase intestinum and bloodSS; Dachengqitang can increase SS,decrease SP and VIP of intestinum;Guipitang can increase SS of bkook decrease SP of intestinum and blood; Wendantang can increase SS of intestine decrease VIP of intestinum and blood. Conclusion: Four Treatment Recipe Durg To Spleen-stomach can change the content of peptide at differential level. May be this is One biological cause that Treatment Recipe Durg To Spleen-stomach has two action on psychsis and digestive disease.