膝骨性关节炎软骨下骨髓水肿样变的研究进展

膝骨性关节炎相关的骨髓水肿样变(knee osteoarthritis-associated bone marrow edema-like lesions,KOA-BMLs)是一种常见的MRI影像学特征,主要表现为T2成像上软骨下骨的异常骨髓高信号.KOA-BMLs的形成可能与下肢力线以及软骨下骨灌注异常有关,而相关的...

Research progress of bone marrow edema-like lesions in knee osteoarthritis

Knee osteoarthritis-associated bone marrow edema-like lesions(KOA-BMLs) is a common MRI imaging feature,which is mainly manifested as abnormal bone marrow hyperintensity in subchondral bone on T2 imaging. The formation of KOA-BMLs may be related to the abnormality of lower limb force line and subchondral bone perfusion,and related histopathological studies showed that the remodeling of bone and bone marrow in these damaged areas was abnormally increased. In KOA patients,the size of BMLs can fluctuate or even disappear in a relatively short period of time,and was closely related to pain,subchondral bone cyst formation,and the progression of KOA. However,the current treatment methods for KOA-BMLs are limited,and there is no uniform guideline or expert consensus,mainly including medication,physical therapy and surgical treatment. This article reviews the research progress of the disease characteristics and treatment of KOA-BMLs in order to provide guidance for the clinical diagnosis and treatment of KOA-BMLs.