| 氯诺昔康在围手术期的应用进展 |
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| 引用本文： | 陈小非,郭建荣. 氯诺昔康在围手术期的应用进展[J]. 中国临床药理学与治疗学, 2008, 13(1): 16-20 |
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| 作者姓名： | 陈小非 郭建荣 |
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| 作者单位： | 宁波大学医学院附属李惠利医院麻醉科,宁波,315040,浙江 |
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| 摘 要： | 氯诺昔康是一种新型的非甾体类抗炎药,其不仅可抑制环氧化酶的活性,还可抑制术后的免疫损伤,其超前镇痛、术中及术后的镇痛疗效与阿片类药物相似,可明显减少阿片类镇痛药物的用量。同时氯诺昔康具有半衰期短、不良反应少、耐受性良好等优点,在围手术期可提供快速而稳定的镇痛效果。
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| 关 键 词： | 氯诺昔康 围手术期 镇痛 非甾体抗炎药 |
| 文章编号： | 1009-2501（2008）01-0016-05 |
| 收稿时间： | 2007-10-16 |
| 修稿时间： | 2007-11-30 |
Advancement of perioperative application of lornoxicam |
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| CHEN Xiao-fei,GUO Jian-rong. Advancement of perioperative application of lornoxicam[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(1): 16-20 |
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| Authors: | CHEN Xiao-fei GUO Jian-rong |
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| Affiliation: | (Department of Anesthesiology, Affiliated Li Hui-li Hospital of Medical College of Ningbo University, Ningbo 315040, Zhejiang, China) |
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| Abstract: | Lornoxicam is a new non-steroidal anti-inflammatory drug,it can inhibit the activity of cyclooxygenases and the immunologic injury afteroperation.Its efficacies on preoperative,operative period and postoperative analgesia are similar to those of opioid.Lornoxicam can decrease the dosage of opioid drugs and has the good qualities of short half-life,few adverse effects and satisfactory tolerance.Lornoxicam can provide rapid and stable analgesic effect in perioperative phase. |
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| Keywords: | lornoxicam perioperative phase analgesia non-steroidal anti-inflammatory drug |
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