青壮年危重症甲型H1N1肺炎的影像与病理

目的：探讨青壮年危重症甲型H1N1肺炎影像表现及病理特征。方法：对4例青壮年甲型HINI死亡病例影像表现与尸检病理资料进行回顾性分析。4例患者均行DR胸片检查,其中1例行胸部CT扫描。结果：1例早期显示两侧中下肺野多发片絮状密度增高影,主要累及内中带;1例早期显示两侧中下肺野多发斑片状密度增高影,第5天双肺多发实变阴影,以双肺门外为著,呈＂蝶翼状＂,可见颈部皮下积气;1例早期显示两肺多发大片实变影,主要累及两侧中下肺野。第6天显示双肺广泛实变阴影,并累及肺外带及两上肺。颈部及胸部可见皮下积气;1例早期显示两肺散在多发片絮状密度增高影,第6天显示两下肺呈大片状实变影。病理对照研究提示影像表现的病理基础是肺泡壁坏死,肺透明膜形成,炎细胞浸润。结论：青壮年危重症甲型H1N1肺炎影像表现具有一定特征性,但缺乏特异性,明确诊断需结合临床与病理检查。

Image and pathological analysis of the adolescent patients with severe influenza A H1N1 pneumonia

Objective:To investigate the radiological manifestations and pathological characteristics of the patients with severe adolescent Influenza A H1N1.Methods:Radiological features and histopathological results from autopsy of 4 young patients dead of severe radiological manifestations were retrospectively analyzed.All 4 patients had DR examinations and one of them also had chest CT scanning.Results:One case showed in the early stage multiple floccule shadows of high density in the middle and inferior lung field...