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Imbalance in the antioxidant defense system as a possible cause of decreased compensatory and adaptive reserves in youths with mitral valve prolapse
Authors:S. A. Chepurnenko
Affiliation:(1) Rostov State Medical University, Russia;(2) Rostov Regional Clinical Hospital, Russia;(3) Rostov Regional Center of Cardiology and Cardiovascular Surgery, Russia
Abstract:An imbalance in the first line of the antioxidant defence and hyperactivity of the glutathione-dependent system were revealed in 137 youths with mitral valve prolapse. Increased activities of superoxide dismutase and glutathione reductase (by 6 and 1.82–2.10 times, respectively) can serve as an additional diagnostic criterion of decreased compensatory reserves in patients with mitral valve prolapse. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 5, pp. 519–521, May, 2007
Keywords:mitral valve  glutathione reductase  catalase  superoxide dismutase
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