| 兔急性颅高压时颅内容积与压力的关系 |
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| 引用本文： | 殷杰,虞佩兰,杨于嘉,青义学.兔急性颅高压时颅内容积与压力的关系[J].中南大学学报(医学版),1987(2). |
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| 作者姓名： | 殷杰 虞佩兰 杨于嘉 青义学 |
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| 作者单位： | 湖南医学院第一附属医院儿科
(殷杰，虞佩兰，杨于嘉)，湖南医学院数学教研室(青义学) |
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| 摘 要： | 作者在以往的颅高压动物实验中,观察到容积-压力的关系为-S 形曲线。通过数学推导,提出颅内容积-压力关系的方程式:p=b/(1+Ce~(-Mv))(其中 C 和 M 为常数,b 为颅内压的峰值)。然后通过对8只免采用侧脑室持续灌注生理盐水的方法,引起急性颅高压,考察其容积-压力变化,结果符合上述方程式表达的关系。
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| 关 键 词： | 颅内压 模型 理论 |
APPROACH TO VOLUME-PRESSURE RELATIONSHIP IN ACUTE INTRACRANIAL HYPERTENSION IN RABBITS |
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| Yin Jie,Yu Peilan,Yang Yujia.APPROACH TO VOLUME-PRESSURE RELATIONSHIP IN ACUTE INTRACRANIAL HYPERTENSION IN RABBITS[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1987(2). |
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| Authors: | Yin Jie Yu Peilan Yang Yujia |
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| Institution: | Yin Jie,Yu Peilan,Yang Yujia Department of Pediatrics,The First Affiliated Hospital,Hunan Medical CollegeQing Yixue Department of Maths,Hunan Medical College |
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| Abstract: | The previous experiments on intracranial hypertention showed that thevolume-pressure relationship seemed to be a S-shaped curve prima ily.Through mathematic integration a formula of volume-pressure relatonship asP=b/(1+Ce~(-Mv))(C and M are contants,b is the maximal value of ICP after thevolume increases continuously)was derived.8 rabbits were treated bycontinuous infusion of normal saline to the lateral ventricle to induceintracranial hypertension,the intracranial pressure increment was monitoredto testify the proposed formula.The results showed that the formula iscompatible. |
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| Keywords: | Intracranial pressure Models theoretical |
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