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血管性痴呆的治疗进展
引用本文:徐群 李焰生. 血管性痴呆的治疗进展[J]. 国外医学:脑血管疾病分册, 2005, 13(9): 681-685
作者姓名:徐群 李焰生
作者单位:上海交通大学医学院附属仁济医院神经内科,200127
基金项目:上海市科委重大攻关项目(03DZ19704)
摘    要:血管性痴呆的治疗包括预防和对症治疗。对症治疗的药物涉及多种作用机制,包括胆碱酯酶抑制、N-甲基-D-天冬氨酸受体拮抗、微循环改善和神经保护等。文章从循证医学角度,对证据级别较高的临床研究进行了综述,以阐明血管性痴呆治疗的现状、存在的问题和将来的研究方向。

关 键 词:血管性痴呆 治疗 临床试验
收稿时间:2005-07-30

1herapeufic Progress in Vascular Dementia
Qun Xu, Yan-Sheng Li. 1herapeufic Progress in Vascular Dementia[J]. Foreign Medical Sciences Cerebrovascular Diseases, 2005, 13(9): 681-685
Authors:Qun Xu   Yan-Sheng Li
Affiliation:Department of Neurology, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
Abstract:The treatment of vascular dementia include prevention and symptomatic treatment. The medicines of symptomatic treatment involve in many mechanisms, including cholinesterase inhibitors, N-methyl-D-asparate receptor antagonists, microcirculation-improving agents and neuroprotectants, etc. From the view of evidence-based medicine, the article reviews some clinical trials that offered higher grade evidence to existing problems and the future direction of study illustrate the present therapeutic status, the in vascular dementia.
Keywords:vascular dementia    treatment    clinical trial
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