2微米激光与等离子电切治疗非肌层浸润性膀胱肿瘤疗效比较的Meta分析

目的比较2微米激光与等离子电切治疗非肌层浸润性膀胱肿瘤的疗效。方法收集已发表的关于2微米激光和等离子电切治疗非肌层浸润性膀胱肿瘤的国内外文献,针对结果进行统计学综合（Meta）分析。采用优势比（OR）及95％置信区间（95％CI）作为评价比较疗效,统计学分析采用Revman4．2软件。结果共5篇文献符合标准纳入,177例2微米激光组和168例等离子电切组进行分析。Meta分析显示：两组比较肿瘤的复发和手术时间的差异均无统计学意义（P〉0．05）,2微米激光组并发症少于等离子电切组,差异有高度统计学意义（P〈0．01）。结论2微米激光治疗非肌层浸润性膀胱肿瘤安全可靠,与等离子电切比较,在避免并发症方面有一定优势。

Comparison of 2 micron laser resection and plasmakinetic resection for non-muscle invasive bladder tumor: Meta-analysis

Objective To compare the efficacy of 2 micron laser resection and plasmakinetic resection for superficial bladder tumor. Methods Retrieved published comparative studies 2 micron laser resection and plasmakinetic resection for superficial bladder tumor, and pooled the data from eligible studies （Meta-analysis）. Odds ratio （OR） and its 95% confidence interval （C/） were used as the measurement parameter of efficacy comparison. The statistical analyses were performed using Revman 4.2 software. Results Five trials including 177 cases were treated with 2 micron laser resec- tion and 168 cases with plasmakinetic resection. Pooling data showed the operative time and postoperative recurrence were not significantly different between the 2 groups （P〉 0.05）, however, compared with elect plasmakinetic resection group, fewer complications in 2 micron laser group, the difference was statistically significant （P 〈 0.01）. Conclusion 2 micron laser resection of superficial bladder tumor is safe, compared to plasmakinetic resection of bladder tumors, this surgery has some advantages on avoiding complications.