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Validation of the French version of the Childhood Health Assessment Questionnaire (CHAQ) in juvenile idiopathic arthritis
Authors:Pouchot Jacques,Larbre Jean-Paul,Lemelle Irène,Sommelet Danièle,Grouteau Eric,David Louis,Duquesne Agnès,Deslandre Chantal Job,Koné Paut Isabelle,Pillet Pascal,Goumy Laurence,Barbier Catherine,Guyot Marie-Hélène,Mazingue Françoise,Laloum Sylvie Gandon,Fischbac Michel,Quartier Pierre,Guyot Claude,Jean Sylvie,Legall Edouard,Plouvier Emmanuel,Bost Michel,de Lumley Lionel,Brégeon Christian,Guillemin Francis,Coste Joël,Prieur Anne-Marie  Pediatric Rheumatology Interational Trials Organisation Qualité de Vie en Rhumatologie Group
Affiliation:1. Internal medicine department, Médecine Interne, Hôpital Louis Mourier, 178, rue des Renouillers, Colombes, France;2. Hospices Civils, Lyon, France;3. CHU Brabois, Nancy, France;4. Hôpital Purpan, Toulouse, France;5. Hôpital Cochin, Paris, France;6. Hôpital Nord, Marseille, France;7. Hôpital Pellegrin, Bordeaux, France;8. CHU d’Angers, Angers, France;9. Hôpital Jeanne de Flandre, Lille, France;10. CHU de Caen, Caen, France;11. Hôpital de Hautepierre, Strasbourg, France;12. Hôpital Necker, Paris, France;13. Hôpital Mère Enfant, Nantes, France;14. Hôpital Sud, Rennes, France;15. Hôpital Saint Jacques, Besançon, France;16. Hôpital Nord, Grenoble, France;17. Hôpital Dupuytren, Limoges, France;18. Ecole de Santé Publique, UPRES EA 1124, Faculté de Médecine, Vandoeuvre, France;19. Département de Biostatistique et d''Informatique Médicale, Hôpital Cochin, Paris, France;1. Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3 Minami-ku, Hiroshima, 734-8553, Japan;2. Department of Radiation Biophysics, Research Institute for Radiation Biology and Medicine (RIRBM), Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8551, Japan;3. Phoenix Leader Education Program (Hiroshima Initiative) for Renaissance from Radiation Disaster, Hiroshima University, Kasumi 1-2-3 Minami-ku, Hiroshima, 734-8553, Japan;4. Department of Radiation Oncology, Hiroshima University Hospital, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8551, Japan;5. Department of Radiation Oncology, Institute of Biomedical and Health Sciences, Hiroshima University Hospital, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8551, Japan;1. Dipartimento di Fisica e Chimica, Università di Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy;2. Gruppo V Sezione INFN, Catania, Italy;3. Dipartimento Energia, Ingegneria dell’Informazione e Modelli Matematici, Università di Palermo, Viale delle Scienze, Ed. 6, I-90128 Palermo, Italy;4. Dipartimento di Chimica, Università di Pavia, V.le Taramelli, 12 Pavia, Italy and INFN, Sezione di Pavia, Pavia, Italy.;1. School of Nursing, University of Wollongong, Northfields Ave, Wollongong, NSW 2522, Australia;2. COORDINARE—South Eastern NSW Primary Health Network, North Wollongong NSW 2500, Australia
Abstract:OBJECTIVES: To translate, cross-culturally adapt, and validate the functional disability tool Childhood Health Assessment Questionnaire (CHAQ), a variant of the Health Assessment Questionnaire (HAQ), in children with juvenile idiopathic arthritis (JIA). CHILDREN AND METHODS: The disability index is the mean of the scores on the eight domains of the CHAQ and can range from 0 (no disability) to 3 (maximum disability). The CHAQ was first translated into French and adapted, then validated in a multicenter cross-sectional study in 306 children with JIA (systemic onset, 23%; polyarticular onset, 22%; extended oligoarticular subtype, 25%; and persistent oligoarticular subtype, 30%). RESULTS: Overall CHAQ scores discriminated between the four JIA subtypes (systemic: 1.1 +/- 0.9; polyarticular: 0.8 +/- 0.7, extended oligoarticular 0.8 +/- 0.7, and persistent oligoarticular: 0.4 +/- 0.5 [P < 0.0001]). Reproducibility evaluated by test-retest at a 7-day interval was excellent (intraclass coefficient, 0.91), as was agreement between the Parent's and Children's versions of the questionnaire (intraclass coefficient, 0.89). Significant correlations were found between the overall CHAO score and variables reflecting disease severity (joint counts, physician's and parent's global assessments, and erythrocyte sedimentation rate), indicating excellent convergent validity of the tool. CONCLUSION: The French version of the CHAQ displays good psychometric characteristics, although its sensitivity to change remains to be established. The French version of the CHAO should prove useful in international studies and can be expected to be helpful for monitoring individual patients with JIA.
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