北京地区5万例新生儿“甲低”足跟血促甲状腺素筛查结果分析

采用干血滴纸片法测新生儿出血后７２小时足跟血的促甲状腺素作为筛选指标。共筛选新生儿５１５８２名，超出筛查均值的异常者随访昨查血清三碘甲状腺原氨酸，甲状腺素及ＴＳＨ含量，查出先天性甲低患儿１０名，提示检测足跟血中的ＴＳＨ含量作为筛查指标是可靠的。

Screening for hypothyroidism in 51582 newborns from heel blood

51582 newborns were screened from january 1993 to june 1996 for hypothyroidism and 10 patients were identibied. 72 hours after birth were adopted for diagnosis of hypothyroidism. RIA and IRMA method was used for their determination. If TSH level is over cutoff va1ue, T3 T4 TSH level in vein blood should be further measuremented. The result showed that TSH screening method in heel blood as screen standed is reliable. Aim significance and method of screen were explored. Detected infants with hypothyroidism were treated with thyroid extract tablets. Physical and mental development of 10 patients showed no difference from normal children of the same age.