2269例新生儿脐带血染色体分析

为了调查北京市西城区展览路地区新生儿染色体畸变的发生率，有效地提高优生优良工作，我室自１９９１年９月至１９９６年９月，对我院妇产科连续出生的新生儿抽取脐带血２２６９例，进行染色体核型，分析，男婴１１１２例，女婴１１５７例。其中染色体畸变儿２２例，发生率０．９７％。资料表明母龄与染色体畸变的发生率有关系，此外与遗传因素及环境也有密切关系。

Chromosomal analysis of umbilical cord blood of 2269 newborn infants

From September 1991 to September 1996 our laboratory tested umbilical cord blood from 2269 newborn infants in the Department of Gynaecology and Obsterics of Zhanlanlu Hospital for women and Infants. We made karyotype analyses of chromosomes of this blood. There were altogether 1112 boys and 1157 girls. OF them, 89 have physical defects, and display intrachromosomal aberration (13 boys and 9 girls). The incidence is 0.97 percent: 69 show congenital maleformation, 31 boys and 36 girls. The incidence of this is 2. 95 percent.The data indicates that the incidence of intrachromosomal aberration is obviously affected by the mother's age, but it is also affected by genetic and environmental factors.