Dynorphin-A immunoreactive terminals on the neuronal somata of rat mesencephalic trigeminal nucleus |
| |
| Authors: | K Yamada H Park S Sato M Onozuka K Kubo T Yamamoto |
| |
| Institution: | 1. Department of Physiology and Neuroscience, Kanagawa Dental College, Yokosuka 238-8580, Japan;2. Department of Craniofacial Growth and Development Denstistry, Kanagawa Dental College, Yokosuka 238-8580, Japan;3. Research Center of Brain and Oral Science, Kanagawa Dental College, Yokosuka 238-8580, Japan;4. Department of Oral Anatomy, Division of Oral Structure, Function and Development, Asahi University School of Dentistry, Mizuho 501-0296, Japan;5. Department of Human Biology, Kanagawa Dental College, Yokosuka 238-8580, Japan |
| |
| Abstract: | Dynorphin-A-like immunoreactivity was investigated in the rat mesencephalic trigeminal nucleus (Mes 5) at the light and electron microscopic levels. Dynorphin-A immunoreactive fibers and puncta, likely representing nerve terminals, were observed throughout rostrocaudal extension of the Mes 5 at the light microscopic level. Within the rostrocaudal extension, more abundant fibers and puncta were localized in the midbrain–pontine junction and pontine areas than in the midbrain area. At the electron microscopic level, dynorphin-A immunoreactive synapses were observed on the somata of Mes 5. Dynorphin-A-like immunoreactivity tended to be restricted to dense-cored vesicles in the synapses. These results suggest that dynorphin-A-containing fiber systems affect mastication through the Mes 5. |
| |
| Keywords: | Dynorphin Mesencephalic trigeminal nucleus Mastication |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
