| 同型半胱氨酸血症的治疗概况及进展 |
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| 引用本文： | 于立妍,王华亭,王红艺,陈立光. 同型半胱氨酸血症的治疗概况及进展[J]. 国外医学:老年医学分册, 2010, 31(5): 207-210 |
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| 作者姓名： | 于立妍 王华亭 王红艺 陈立光 |
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| 作者单位： | 于立妍,Yu Liyan(潍坊医学院,潍坊,261053,中国);王华亭,Wang Huating(山东大学附属济南市中心医院心内科,济南,250013,中国);王红艺,Wang Hongyi(山东省千佛山医院,济南,250014,中国);陈立光,Chen Liguang(山东省医学影像学研究所,济南,250021,中国) |
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| 基金项目： | 山东省科技攻关计划项目 |
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| 摘 要： | 同型半胱氨酸是一种含巯基的氨基酸，它是蛋氨酸和半胱氨酸过程中的一个重要的中间产物，其本身并不参加蛋白质的合成。当与同型半胱氨酸代谢有关的酶或辅助因子缺乏使同型半胱氨酸代谢受阻时，就会导致高同型半胱氨酸血症。近年来大量研究证实高同型半胱氨酸与心脑血管疾病、外周血管疾病、神经系统退行性疾病、糖尿病等发病高度相关，同型半胱氨酸已成为心脑及外周血管疾病的危险因素及预测指标。本文将同型半胱氨酸血症的近年治疗概况及进展作一综述。
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| 关 键 词： | 同型半胱氨酸血症 治疗 心血管疾病 脑血管疾病 外周血管疾病 |
Progress in the Treatment of the Patients with Homocysteinemia |
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| Yu Liyan,Wang Huating,Wang Hongyi,Chen Liguang. Progress in the Treatment of the Patients with Homocysteinemia[J]. Foreign Medical Sciences(Geriatrics), 2010, 31(5): 207-210 |
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| Authors: | Yu Liyan Wang Huating Wang Hongyi Chen Liguang |
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| Affiliation: | Yu Liyan Wang Huating Wang Hongyi Chen Liguang(1.Weifang Medical College, Weifang 261053, China 2 Department of Cardiology, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China; 3 Shandong Provincial Qianfoshan Hospital, Jinan 250014, China 4Shandong Provincial Medical Imaging Research Institute, .linan 250021, China)) |
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| Abstract: | Homocysteine, a sulfur amino acid, is an important intermediate metabolite of methionine and cysteine, it does not participate in protein synthesis. When Hey metabolism is blocked because of the lack of the enzyme or cofactor it will cause hyperho- mocysteinemia. In recent years numerous studies confirm that high homocysteine is highly related to cardiovascular and eerebrovaseular diseases, peripheral vascular diseases, neurodegenerative diseases, diabetes and so on. Hcy has become a risk factor and predictor of the heart, brain and peripheral vascular diseases. This paper reviews the progress in the treatment of the patients with homoeys- teinemia in recent years. |
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| Keywords: | Hyperhomocysteinemia Treatment Cardiovascular disease Cerebrovascular disease Peripheral vascular disease |
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