脑室-腹腔分流术后感染的预防及治疗

目的探讨脑室-腹腔分流术后感染的诊断及其防治方法。方法回顾性分析脑室-腹腔分流术后发生感染的12例临床资料。结果12例患者行脑脊液细菌培养,凝固酶阴性葡萄球菌6例,金黄色葡萄球菌4例,奇异变形菌1例,粪肠球菌1例;经治疗后症状均明显改善,随访发现2例重度感染患者,感染控制后遗有癫痫、认知障碍和精神运动性阻滞等后遗症。结论颅内感染是脑积水分流术后最常见、最严重的并发症之一,对分流术后感染的患者进行及时有效的预防和治疗是减少后遗症,提高患者生活质量的关键。

Prevention and Treatment of Infection in Ventriculo-peritoneal Shunts

OBJECTIVE To study the diagnosis,prevention and treatment of infection in ventriculo-peritoneal shunts. METHODS A retrospective review of the clinical datas of 12 patients who were complicated by fever after undergoing ventriculo-peritoneal shunt has been analyzed. RESULTS Cerebrospinal fluid(CSF) bacterial culture showed that the causative organisms were coagulase-negative staphylococci in 6 cases,Staphylococci aureus in(4 cases),Proteus mirabilis in 1 case and Enterococcus faecalis in 1 case.The symptoms of all the patients have improved evidently after treatment.Two cases with serious infection have been found that some sequelae occurred,including epilepsy,cognitive disorder,and psychomotor retardation. CONCLUSIONS Intracranial infection is one of the most serious and commonest complications in ventriculo-peritoneal shunts.The timely and effective prevention and treatment of infection in ventriculo-peritoneal shunts are of consequences to reduce sequelae and improving quality of life in patients.