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当归总酸抗心律失常作用的研究及其它作用的观察
引用本文:朱玉真 杨庆利. 当归总酸抗心律失常作用的研究及其它作用的观察[J]. 兰州大学学报(医学版), 1989, 15(3): 125-128
作者姓名:朱玉真 杨庆利
作者单位:兰州医学院药理教研室,兰州医学院药理教研室,兰州医学院药理教研室
摘    要:

关 键 词:当归 当归总酸 抗心律失常

A Preliminary Study on the Antiarrhythmic Actions of the Total Organic Acid Constituents of Gangsu Danggui
Zhu Yuzhen,et al,. A Preliminary Study on the Antiarrhythmic Actions of the Total Organic Acid Constituents of Gangsu Danggui[J]. Journal of Lanzhou University (Medical Sciences), 1989, 15(3): 125-128
Authors:Zhu Yuzhen  et al  
Abstract:The total organic acid constituents of Dang-gui roots on the antiarrhyth- mic actions in rabbits and rats were studied. Experiments indicated that the total organic acid constituents (2%-1.0ml/kg, ip in rats or 20mg/kg, iv in rabbits)produced obvious pro- tective effects on adrenaline-chloro- form(rabbits), aconitine(rats)and BaC12 (rats)induced arrhythmias by shortening the total duration of them. Total organic acid constituents di- minished also the spontaneous activ- ity and increased the ability of hyp- oxia tolerance in mice. ECG in una- nesthetized rabbits after 20mg/kg to- tal organic acid constituents admini- stration iv, characterized by a leng- thening of PR interval with the red- uction of amplitude.
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