Nonrandom t(1;22)(p12-p13;q13) in acute megakaryocytic malignant proliferation |
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| Authors: | A Baruchel M T Daniel G Schaison R Berger |
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| Affiliation: | Service D'Hématologie Pédiatrique, H?pital Saint-Louis, Paris, France. |
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| Abstract: | A case of acute megakaryocytic leukemia (M7) and one of acute myeloid hemopathy affecting megakaryocytic and erythrocytic cell lineages in infants are reported. Both patients had t(1;22)(p12-p13;q13). This translocation was previously observed in a congenital M7 leukemia. These studies suggest that t(1;22) translocation can be nonrandom in M7. |
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