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Bioequivalence |
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| Authors: | Rescigno Aldo |
| Institution: | (1) School of Pharmacy, University of Parma, Parma, Italy;(2) Department of Pharmacokinetics, Genentech, Inc., 406 Point San Bruno Boulevard, South San Francisco, California, 94080-4918 |
| Abstract: | The bioequivalence of two formulations of the same drug may be determined by evaluating the similarity of their respective plasma concentration curves. The similarity of two plasma concentration functions can be measured by an index called the bioequivalence index. This paper shows how such an index may be defined and calculated. |
| Keywords: | bioequivalence bioavailability plasma concentration function AUG |
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