| 实验性消化道溃疡上皮淋巴细胞毒活性的变化 |
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| 引用本文： | 刘北星,吕昌龙. 实验性消化道溃疡上皮淋巴细胞毒活性的变化[J]. 中国免疫学杂志, 1999, 15(3): 129-131 |
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| 作者姓名： | 刘北星 吕昌龙 |
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| 作者单位： | 中国医科大学免疫研究室,沈阳,110001 |
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| 摘 要： | 了解消化道溃疡机体的免疫功能变化。方法应用生物学测定法检测了水浸限制刺激诱发的Ｃ５７ＢＬ／６小鼠消化道溃疡动物模型肠上皮淋巴细胞和脾淋巴细胞的细胞活性的变经。结论肠上皮淋巴细胞活性在消化道溃疡发生后的一定期间内有升高，这一升高可能对肠道的功能具有保护作用。
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| 关 键 词： | 肠上皮淋巴细胞 杀伤活性 消化性溃疡 |
The change of cytotoxicity of intestinal intraepithelial lymphocytes from mice with experimental digestive ulcer |
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| LIU Bei-Xing,L Chang-Long. The change of cytotoxicity of intestinal intraepithelial lymphocytes from mice with experimental digestive ulcer[J]. Chinese Journal of Immunology, 1999, 15(3): 129-131 |
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| Authors: | LIU Bei-Xing L Chang-Long |
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| Affiliation: | LIU Bei-Xing,L(U) Chang-Long |
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| Abstract: | Objective:In order to understand immunological changes in the body with digestive ulcer.Methods:The cytotoxity of intestinal intraepithelial lymphocytes(IELs)in C57BL/6 mice with digestive ulcer induced by water immersion were examined by biological assay technique.Results:It was showed that the cytotoxity of IELs was enhanced to a peak in 2 days and down back to the normal in 7 days after the stress and that the cytotoxity of spleen cells was lower than that of normal and could not revive to normal level on the 9th day. Conclusion:the cytotoxity of IELs was increased in a certain period of time after the ulcer,indicating IELs may play a protective role in digestive tract. |
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| Keywords: | Water immmersion restrain stress Intestinal intraepithelial lymphocyte(IEL) Cytotoxity |
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