| 乙醇对习惯性流产夫妇外周血淋巴细胞染色体的致畸敏感性研究 |
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| 引用本文： | 王应雄,翁亚光,张湘蜀,吴春英,郑增淳.乙醇对习惯性流产夫妇外周血淋巴细胞染色体的致畸敏感性研究[J].重庆医科大学学报,1988(4). |
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| 作者姓名： | 王应雄 翁亚光 张湘蜀 吴春英 郑增淳 |
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| 作者单位： | 重庆医科大学计划生育系遗传与优生教研室
(王应雄，翁亚光，张湘蜀，吴春英)，重庆医科大学计划生育系遗传与优生教研室(郑增淳) |
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| 摘 要： | 本文对12例习惯性流产夫妇外周血淋巴细胞染色体作了乙醇致畸敏感性研究.以SCE、微核及其染色体畸变为检测指标.结果提示乙醇是一种较强的染色体致畸剂.总体讲,习惯性流产夫妇细胞染色体稳定性较差,并对乙醇的致畸效应较常人更为敏感
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| 关 键 词： | 乙醇 习惯性流产 染色体畸变 优生咨询 |
STUDIES ON EFFECT OF ALCOHOL ON THE SENSITIVITY OF CHROMOSOMAL ABERRATIONS IN THE CULTURED LYMPHOCYTSE OF THE COUPLES WITH HABITUAL ABORTION |
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| Institution: | Department of Family Planning. Wang Yingxiong |
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| Abstract: | Twelve cases with history of habitual abortion were studied for the sensitivity of chromosomal aberrations in their lymphocytes. We analyzed the frequencies of SEC, chromosomal aberrations and micronucleus. It shows that alcohol is a mutagen inducing chromosomal aberrations. The chromosomes in the couples with habitual abortions are more unstable and more seneitive to alcohol than those of normal persons |
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| Keywords: | Alcohol Habitual abortion Chromosomal aberration Eugenics counseling |
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