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鼻腔鼻窦肾细胞样腺癌临床病理观察
引用本文:张森,张安莉,吴海波. 鼻腔鼻窦肾细胞样腺癌临床病理观察[J]. 诊断病理学杂志, 2021, 0(2): 81-84
作者姓名:张森  张安莉  吴海波
作者单位:中国科学技术大学附属第一医院(安徽省立医院)临床病理中心规培基地;中国科学技术大学附属第一医院(安徽省立医院)临床病理中心
基金项目:安徽省自然科学基金(1908085MH281);中央高校基本科研业务费专项资金(WK9110000042)。
摘    要:目的 探讨鼻腔鼻窦肾细胞样腺癌(SNRCLA)的临床病理学特征.方法 分析1例SNRCLA的病理诊断及鉴别诊断,并结合文献进行复习.结果 患者男性,64岁,右鼻腔肿物.组织学示肿瘤相似于透明细胞型肾细胞癌,由胞质透亮的瘤细胞组成,间质富于毛细血管.免疫组化示肿瘤细胞CK7、CK、vimentin、S100、CAⅨ、SO...

关 键 词:鼻腔鼻窦  低级别  肾细胞样腺癌

Clinicopathological features of sinonasal renal cell-like adenocarcinoma
ZHANG Sen,ZHANG An-li,WU Hai-bo. Clinicopathological features of sinonasal renal cell-like adenocarcinoma[J]. Chinese Journal of Diagnostic Pathology, 2021, 0(2): 81-84
Authors:ZHANG Sen  ZHANG An-li  WU Hai-bo
Affiliation:(Training Base of Clinical of Pathology,the First Afiated Hospital of USTC、Dirision of life Sciences and Medicine,Unitersity of Science and Technology of China,Hefei 230036,China;Departmen of Pathology,the First Afiliated Hospital of USTC,Dinision of Life Seciences and Medicine,University of Science and Technology of China,Hefei,230036,China)
Abstract:Objective To investigate the clinicopathological features of sinonasal renal cell-like adenocarcinoma(SNRCLA).Methods The pathological diagnosis and differential diagnosis of one case of SNRCLA were analyzed,and the literature was reviewed.Results A 64 years old male presented with a right nasal mass.Histologically,the tumor was similar to clear cell renal cell carcinoma of the kidney.It was composed of tumor cells with clear cytoplasm and rich capillary in stroma.Immunohistochemical staining showed that CK7,CK,vimentin,S100,CA IX,SOX10,EMA,MUC-1 and Dog-1 were all positive,while PAX8,CD10 and RCC were negative.Conclusion SNRCLA is a rare low-grade primary malignant tumor of sinonasal tract.It is easy to be confused with clear cell renal cell carcinoma and other tumors in morphology.Immunohistochemistry is helpful in the diagnosis of SNRCLA.
Keywords:Sinonasal tract  Low-grade  Renal cell-like adenocarcinoma
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