| 慢性特发性血小板减少性紫癜与心内直视术 |
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| 引用本文： | 许咏冬,倪一鸣. 慢性特发性血小板减少性紫癜与心内直视术[J]. 中国胸心血管外科临床杂志, 2003, 10(3): 200-202 |
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| 作者姓名： | 许咏冬 倪一鸣 |
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| 作者单位： | 1. 浙江省丽水市中心医院,心胸外科,323000
2. 浙江大学医学院附属第一医院,心胸外科,杭州,310003 |
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| 摘 要： | 合并慢性特发性血小板减少性紫癜(ITP)的心脏病患者，接受体外循环(CPB)心内直视术后，会面临较大的出血风险。通过术前应用激素、大剂量静脉注射γ-球蛋白、达那唑，术前或同期行脾切除术，术中应用膜式氧合器、抑肽酶和／或止血环酸、肝素涂敷CPB管道、离心泵、自体血液回收、常温以及CPB结束后输注血小板等综合措施，术后可明显降低此类患者的出血风险。
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| 关 键 词： | 慢性特发性血小板减少性紫癜 心内直视术 心脏病 体外循环 合并症 |
| 文章编号： | 1007-4848(2003)03-0200-03 |
| 修稿时间： | 2002-12-02 |
Chronic idiopathic thrombocytopenic purpura and open heart surgery |
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| XU Yong-dong,NI Yi-ming. Chronic idiopathic thrombocytopenic purpura and open heart surgery[J]. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2003, 10(3): 200-202 |
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| Authors: | XU Yong-dong NI Yi-ming |
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| Affiliation: | XU Yong-dong1,NI Yi-ming2 |
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| Abstract: | The patients of heart diseases combined with chronic idiopathic thrombocytopenic purpura face higher bleeding risk after being performed open heart surgery on cardiopulmonary bypass(CPB). By means of preoperative adrenal corticosteroids, high-dose intravenous gamma-globulin, danazol, preoperative or simultaneous splenectomy, use of membranous oxygenator , intraoperative administration of aprotinin and/or tranexamic acid, heparin-coated CPB ducts, centrifugal pump, Cell Saver, normothermic CPB, and platelets transfusion at the termination of CPB, the risk of bleeding complications in the postoperative period will be significantly lowered. |
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| Keywords: | Idiopathic thrombocytopenic purpura Cardiopulmonary bypass Open heart surgery |
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