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19例颌骨放射性骨坏死的临床总结
引用本文:刘向辉,张森林,黄辉,张纯. 19例颌骨放射性骨坏死的临床总结[J]. 口腔颌面外科杂志, 2009, 19(2)
作者姓名:刘向辉  张森林  黄辉  张纯
作者单位:解放军第八一医院口腔科,江苏,南京,210002;南京军区南京总医院口腔科,江苏,南京,210002
摘    要:目的:总结颌骨放射性骨坏死的诊治特点,探索其预防方法。方法:对1995—2006年间收治的19例颌骨放射性骨坏死病例进行回顾性分析及随访。结果:19例中12例是鼻咽癌放疗后引起的,发生于下颌骨者远多于上颌骨。平均放疗剂量68.1Gy,均为外照射;发生在放射后1~5年间者占80.4%。临床上主要表现为疼痛、感染、组织坏死脱落和张口受限等。在治疗上主要采用以扩大清除坏死组织为主的手术治疗,高压氧作为辅助治疗。结论:放射损害是颌骨放射性骨坏死发生的根本原因,损伤和感染是诱发因素;局部死骨的扩大切除是根治的主要方法;加强口腔护理、避免放疗区的损伤和感染是预防的关键。

关 键 词:放射性骨坏死  颌骨  治疗  预防

Osteoradionecrosis of the Jaws of 19 Cases
LIU Xiang-hui,ZHANG Sen-lin,HUANG Hui,ZHANG Chun. Osteoradionecrosis of the Jaws of 19 Cases[J]. Chinese Journal of Oral and Maxillofacial Surgery, 2009, 19(2)
Authors:LIU Xiang-hui  ZHANG Sen-lin  HUANG Hui  ZHANG Chun
Affiliation:1. Department of Stomatology;The PLA 81st Hospital;Nanjing 210002;2. Department of Stomatology;Nanjing General Hospital of Nanjing Military Command;Jiangsu Province;China
Abstract:Objective: To summarize the diagnosis , therapy and preventive measures of osteoradionecrosis of the jaws (ORNJ). Methods: 19 cases of ORNJ between 1995 and 2006 were retrospectively reviewed. Results: 12 cases were initiated after radiotherapy of nasopharyngeal carcinomas; the lower jaw was far more prevalent than the upper jaw. Average irradiation dose was 68.1 Gy, and all were external irradiation; 80.4% of the cases manifested between 1 to 5 years after radiotherapy.Clinical symtoms included pain, infec...
Keywords:osteoradionecrosis  jaw  therapy  prevention  
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