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Immunochemical identification of organ-specific human placentalαin2-globulin and its content in the amniotic fluid
Authors:D D Petrunin  I M Gryaznova  Yu A Petrunina  Yu S Tatarinov
Institution:(1) Department of Biochemistry and Department of Obstetrics and Gynecology, N. I. Pirogov Second Moscow Medical Institute, USSR
Abstract:An organ-specific human placental agr2, differing immunologically from previously known agr2 and beta1-globulins of pregnancy, agr-fetoprotein, placental lactogen, and chorionic gonadotropin, was identified by immunochemical analysis. The antigen thus discovered is present in large quantities in the placental tissue and amniotic fluid in the early stages of pregnancy, but at parturition its concentration is sharply reduced.Presented by Academician of the Academy of Medical Sciences of the USSR Yu. M. Lopukhin.Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 7, pp. 803–804, July, 1976.
Keywords:human placenta  organ-specific antigen
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