Clinical Impact of Depression in Cirrhosis |
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| Authors: | Joao Miguel Serigado Katherine C Barboza Paula Marcus Samuel H Sigal |
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| Institution: | 1.Division of Gastroenterology and Liver Diseases,Montefiore Medical Center, The Albert Einstein College of Medicine,Bronx,USA;2.Department of Population Health,New York University Langone Medical Center,New York,USA;3.Department of Psychiatry,Montefiore Medical Center, The Albert Einstein College of Medicine,Bronx,USA;4.Montefiore–Einstein Center for Transplantation,Montefiore Medical Center, The Albert Einstein College of Medicine,Bronx,USA |
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| Abstract: | Purpose of ReviewDepression is the most commonly diagnosed psychiatric illness. It is prevalent in most chronic medical conditions and is associated with increased morbidity and mortality. Depression is especially common in patients with cirrhosis.Recent FindingsIn this review, we discuss the prevalence, risk factors, diagnosis, clinical impact, and treatment of depression in cirrhosis. We describe various screening tests important for diagnosis, the interaction of depression with hepatic encephalopathy, and its significant impact on medication adherence, mortality, and caregiver burden.SummaryThese findings highlight the importance of appropriate screening, diagnosis, and treatment of depression in patients with cirrhosis. |
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