脑深部肿瘤立体定向铱-192核素瘤内近距离照射的研究

报告１９９１年１２月～１９９５年１２月用立体定向对脑深部肿瘤１４２例进行了铱１９２后装管置入作了间质内放疗。男１０６例，女３６例，年龄５～７７岁，平均３５．９岁。术后１２０例随访１～４年，平均２．２年，结果显示：平均生存期２６个月，比未经间质内放疗者平均１３个月显著延长，证明铱－１９２瘤内放疗是治疗脑深部肿瘤一种可行有效的方法。

CT Guided Stereotactic Interstitial Iridium 192 Irradiation for Treatment of Brain deep Seated Tumors

CT Guided stereitactic procedures make it easy to place radioactive material in tumors at exact and reproducible sites. A stereotactic program of interstitial iridium 192 radiotherapy in deep seated brain tumors has been applied in 142 cases since December 31, 1992. There were 106 males and 36 females ranging in age from 5 77 years (median 35.9 years). Primary and recurrent tumor sites included the frontal lobe (29), parietal lobe (26) temporal lobe (15), frontoparietal region (20), temporo parietal region (18), parieto occipital region (15), occipital lobe (5) frontotemporal region (13) and cerebellar (2). Stereotactic biopsy were astrocytoma in 80 cases, glioblastoma in 13, oligodendroglioms in 5, ependyma in 2, metastasis in 12, lymphoma in 2, meningicma in 4 pinealocytoma in 13, craniopharyngioma in 5, chordoma in 2, colloid cyst. in 1, engioneoplasm in 1 and medulloblastoma in 2. 120 Patients were up foolowed from 1 to 4 years, with a median of 2, 2 years. Our results showed that the median survival of this group of patients was 26 months which was significantly higher than the mediansurvival of 13 months for a group of similar patients treated whthout an Important boost.