生长抑素及其类似物对肝癌的治疗进展

生长抑素是一种具有广泛生物学活性的物质.近年发现,生长抑素及其类似物能够抑制肿瘤细胞增殖,诱导肿瘤细胞凋亡,不仅能抑制具有神经内分泌功能肿瘤的增殖,对普通的实体瘤亦有抑制作用,已初步应用于临床.现主要综述近年来生长抑素及其类似物在肝癌治疗方面的研究进展,以期为临床治疗肝癌提供新的途径和方法.

Progress of hepatocellular carcinoma by somatostatin and somatostatin anolog

Somatostatin is a kind of cytokine having general biologic activity. Recent studies have shown that somatostatin and somatostatin anolog can inhibit the tumor cell proliferation and induce the tumor cell into apoptosis. Not only can it inhibit proliferation of neuroendocrine tumor, but it has inhibitory action on ordinary solid tumor. Somatostatin and somatostatin anolog in the therapy of hepatocellular carcinoma have been used in clinic. Now this article mainly reviews recent research progress of somatostatin and somatostatin anolog in the therapy of hepatocellular carcinoma,in order to provide new channel and way for the treatment of hepatocellular carcinoma.