Treatment of Secondary Immune Thrombocytopenia with Non-Hodgkin Lymphoma: A Case Report and Literature Review |
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| Authors: | Yuya Kurihara Kazuki Taoka Eri Takagi Kazuhiro Toyama Kumi Nakazaki Mineo Kurokawa |
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| Institution: | 1.Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan; 2.General Education Center, The University of Tokyo Hospital, Japan; 3.Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital, Japan |
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| Abstract: | Secondary immune thrombocytopenic purpura (ITP) with non-Hodgkin lymphoma (NHL) is a rare disease. Although some treatment regimens are available for primary ITP, the treatment strategy for secondary ITP remains unconfirmed. We herein report a 79-year-old man who was diagnosed with secondary ITP with mantle cell lymphoma. Although intravenous immunoglobulin (IVIG) has been considered an effective option for secondary ITP, similar to the treatment of primary ITP, our patient did not benefit from IVIG. A literature review including the current report revealed that IVIG was ineffective in all treated patients. Secondary ITP with NHL should be treated differently from primary ITP. |
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| Keywords: | secondary immune thrombocytopenia intravenous immunoglobulin chemotherapy non-Hodgkin lymphoma |
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