Contractile activity of neonatal heart cells in culture derived from offspring of exercised pregnant rats |
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| Authors: | H. W. Bonner C. K. Buffington J. J. Newman R. P. Farrar D. Acosta |
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| Affiliation: | (1) Department of Physical and Health Education, The University of Texas at Austin, 222 Bellmont Hall, 78712 Austin, TX, USA;(2) Department of Pharmacology, College of Pharmacy, University of Texas, 78712 Austin, Tex., USA |
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| Abstract: | Summary 5-day-old neonatal offspring of exercised or non-exercised pregnant Sprague Dawley rats were used to prepare primary cultures of beating myocardial cells. The cells from the exercise group exhibited a slower beating rate for both single and aggregate cells; a larger cell size; an increased percentage of contracting cells; a greater capacity to form confluent monolayers, and a greater viability. It was concluded that exercise during the period of pregnancy produced morphological alterations in the myocardium of the progeny. |
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| Keywords: | Training Pregnancy Myocardial cell cultures |
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