某城区流动育龄人群血清抗苗勒氏管激素水平的检测结果分析

目的 探讨并分析某城区流动育龄人群血清抗苗勒氏管激素(anti-mullerian hormone,AMH)水平的检测结果.方法选取2016年12月至2017年6月某医院随机抽取的流动育龄期女性200例作为研究对象,采用罗氏化学发光法检测AMH水平,并分析检查结果.结果 200例完成1个月经周期的血清AMH检测,早卵泡期、排卵期、黄体中期血清AMH水平比较,差异无统计学意义(P>0.05);其中69例完成连续2个月经周期的血清AMH检查,两个月经周期间的早卵泡期、排卵期、黄体中期血清AMH水平比较,差异无统计学意义(P>0.05).≤25岁的女性血清AMH水平明显高于26~30岁、31~35岁、36~40岁、41~45岁年龄段女性的血清AMH水平(P<0.05),且两个不同年龄段之间比较差异有统计学意义(P<0.05);Spearman相关分析显示,AMH与年龄呈负相关关系(r=-0.317,P<0.05).结论 流动育龄期女性月经周期内AMH维持稳定水平,另外AMH水平随年龄增加而下降.

Detection of Serum Anti-Mullerian Hormone Levels in Migrating Population with Childbearing Age in a City

Objective To investigate and analyze the detection results of serum anti-Mullerian hormone(AMH) levels in migrating population with childbearing age in a city.Methods A total of 200 migrating women with childbearing age were randomly selected from a hospital from December 2016 to June 2017.AMH levels were detected by Roche chemiluminescence method and the results were analyzed.Results All of the 200 subjects finished a menstrual cycle of serum AMH detection.There were no significant differences in serum AMH levels in the early follicular phase,the ovulation phase and the middle luteal phase(P>0.05).Among them, 69 women completed 2 menstrual cycles of serum AMH detection,and there were no significant differences in serum AMH levels in the early follicular phase,the ovulation phase and the middle luteal phase during the 2 menstrual cycles(P>0.05).AMH levels in women with aged ≤ 25 years old were higher than those in women aged 26 -30 years old,31-35 years old,36-40 years old or 41-45 years old(P<0.05),and there were significant differences between two different age groups(P <0.05).Spearman correlation analysis showed that AMH was negatively correlated with age(r=-0.317,P<0.05).Conclusion AMH is stable in menstrual cycle of migrating women of child-bearing age,and the AMH level decreases with the increase of age.