Integrated screening concept in women with genetic predisposition for breast cancer |
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Authors: | U Bick |
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Institution: | Institut für Klinische Radiologie, Universit?t, Münster, XX
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Abstract: | Summary
Breast cancer is in 5 % of cases due to a genetic disposition. BRCA1 and BRCA2 are by far the most common breast cancer susceptibility
genes. For a woman with a genetic predisposition, the individual risk of developing breast cancer sometime in her life is
between 70 and 90 %. Compared to the spontaneous forms of breast cancer, woman with a genetic predisposition often develop
breast cancer at a much younger age. This is why conventional screening programs on the basis of mammography alone cannot
be applied without modification to this high-risk group. In this article, an integrated screening concept for women with genetic
predisposition for breast cancer using breast self-examination, clinical examination, ultrasound, mammography and magnetic
resonance imaging is introduced.
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Keywords: | Mammography • Ultrasound • Magnetic resonance imaging • Screening • Breast cancer • Genetic disposition |
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