A lasting change in trazodone response after non-convulsive electroshock therapy for medication-resistant senile depression |
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Authors: | HAOWEI SHEN MD SHUICHI AWATA MD MICHIKO KONNO MD MITSUMOTO SATO MD |
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Affiliation: | Department of Psychiatry, Tohoko University School of Medicine, Sendai, Japan |
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Abstract: | Abstract A senile patient showed a dramatic recovery from medication-resistant depression after non-convulsive electro-shock therapy (nc-EST), with a lasting change in response to trazodone, which mainly acts as a serotonin re-uptake inhibitor. This result suggests that a change in the serotonin reuptake mechanism may be involved in the effect of nc-EST on depression. |
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Keywords: | depression electroconvulsive treatment trazodone |
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