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A lasting change in trazodone response after non-convulsive electroshock therapy for medication-resistant senile depression
Authors:HAOWEI SHEN MD    SHUICHI AWATA MD    MICHIKO KONNO MD   MITSUMOTO SATO MD
Affiliation:Department of Psychiatry, Tohoko University School of Medicine, Sendai, Japan
Abstract:Abstract A senile patient showed a dramatic recovery from medication-resistant depression after non-convulsive electro-shock therapy (nc-EST), with a lasting change in response to trazodone, which mainly acts as a serotonin re-uptake inhibitor. This result suggests that a change in the serotonin reuptake mechanism may be involved in the effect of nc-EST on depression.
Keywords:depression    electroconvulsive treatment    trazodone
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