特应性皮炎儿童生活质量调查

目的：特应性皮炎常造成儿童行为、情感、心理发育等方面的异常。本研究旨在调查特应性皮炎幼儿的生活质量。方法：应用儿童特应性皮炎影响量表 (Childhood Atopic Dermatitis Impact Scale，CADIS)调查问卷进行生活质量调查, 并用特应性皮炎评分量表(SCORing Atopic Dermatitis，SCOARD)对特应性皮炎患儿进行临床症状评估。结果：患儿SCORAD评分为56.9±11.1；CADIS评分为38.0±7.9。CADIS与SCORAD存在显著正相关(ρ=0.934,P＜0.05), 其中,与受累面积(ρ=0.581,P＜0.01)、红斑(ρ=0.417,P＜0.01)、糜烂(ρ=0.579,P＜0.01)、水肿丘疹(ρ=0.595,P＜0.01)、渗出结痂(ρ=0.436,P＜0.01)、皮肤干燥(ρ=0.343,P＜0.01)、瘙痒和睡眠减少(ρ=0.0.344,P＜0.05)关系密切。结论：特应性皮炎对患儿生活质量有显著影响, 随着疾病严重程度升高,生活质量逐渐下降。［中国当代儿科杂志，2010，12（5）：351-353］

Quality of life in children with atopic dermatitis

Objective Atopic dermatitis affects children′s behavioral,emotional and psychological development.This study aimed to investigate the quality of life in infants with atopic dermatitis.Methods The quality of life in 43 children with atopic dermatitis between the age of 3-6 months was assessed by the Childhood Atopic Dermatitis Impact Scale(CADIS).The severity of atopic dermatitis was determined by the SCORing Atopic Dermatitis(SCOARD).Results The scores of SCORAD and CADIS in children with atopic dermatitis were 56.9±11.1 and 38.0±7.9 respectively.There was a positive correlation between the CADIS and SCORAD scores(ρ=0.934,P<0.05).The CADIS score was positively correlated with the area of skin lesions(ρ=0.581,P<0.01),erythema(ρ=0.417,P<0.01),excoriations(ρ=0.579,P<0.01),edema/ exanthema papulosum(ρ=0.595,P<0.01),oozing/crusts(ρ=0.436,P<0.01),skin dryness(ρ=0.343,P<0.01),pruritus and sleeplessness(ρ=0.0.344,P<0.05).Conclusions Atopic dermatitis adversely affects the quality of life in children with atopic dermatitis.The worse quality of life is associated with more severe atopic dermatitis.