中国HPV感染面临的问题与挑战

人乳头状瘤病毒（HPV）感染已成为全球女性最严重的疾病负担之一，其不仅可以引起常见的性传播疾病，还与生殖道肿瘤密切相关。尤其是高危型HPV，是导致宫颈癌的最主要因素。虽然HPV感染与宫颈癌的临床研究已成为近十余年的研究热点，但我国有关HPV感染的流行病学、高危型HPV检测在我国宫颈癌筛查中的作用和地位、如何阻断高危型HPV的持续性感染以及HPV疫苗在中国的应用等方面还存在诸多问题与挑战。

The Challenges of HPV Infection in China

Human papillomavirus（HPV） infection has become one of the most serious disease burdens for women. HPV infection not only causes the common sexually transmitted disease（STD），and also closely related to genital tract tumors. Particularly，the persistent infection of high-risk HPV （HR-HPV） is the most important risk factor of cervical cancer. Although the clinical research about HPV infection and cervical cancer has become a hot spot over the past decade，there are still many problems and challenges about the epidemiology of HPV infection，such as the role of HR-HPV testing in cervical cancer screening，how to block the HRHPV persistent infection, and the use of HPV vaccine in China.