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正交试验法优选柴黄清胰活血颗粒水提工艺
引用本文:李静,赵剑,李志,蒲清荣,罗群,任桂林. 正交试验法优选柴黄清胰活血颗粒水提工艺[J]. 中国药业, 2020, 0(5): 89-91
作者姓名:李静  赵剑  李志  蒲清荣  罗群  任桂林
作者单位:西南医科大学附属中医医院
基金项目:泸州市人民政府—西南医科大学联合基金项目[2015LZCYD-S09(1/8)]
摘    要:目的优选柴黄清胰活血颗粒的水提工艺。方法以栀子苷的转移率为评价指标,采用L9(34)正交试验法,考察煎煮时间、浸泡时间、煎煮次数、加水量4个因素对水提工艺的影响,并进行验证试验。结果最佳水提工艺为加10倍量水,浸泡30 min,煎煮3次,每次1.0 h。结论优选的提取工艺合理可行,稳定客观。

关 键 词:柴黄清胰活血颗粒  正交试验  转移率  栀子苷  提取工艺

Water Extraction Process of Chaihuang Qingyi Huoxue Granules by Orthogonal Test
LI Jing,ZHAO Jian,LI Zhi,PU Qingrong,LUO Qun,REN Guilin. Water Extraction Process of Chaihuang Qingyi Huoxue Granules by Orthogonal Test[J]. China Pharmaceuticals, 2020, 0(5): 89-91
Authors:LI Jing  ZHAO Jian  LI Zhi  PU Qingrong  LUO Qun  REN Guilin
Affiliation:(The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University,Luzhou,Sichuan,China 646000)
Abstract:Objective To optimized the water extraction process of Chaihuang Qingyi Huoxue Granules.Methods With the transfer rate of geniposide as an evaluation index,the L9(34)orthogonal test method was used to investigate the effects of four factors:decoction time,soaking time,number of decoctions,and water additions on the water extraction process,and a verification test was performed.Results The best water extraction process was to add 10 times the amount of water,soaked for 30 min,and decoction for3 times,each for 1.0 h.Conclusion The optimal extraction process is reasonable,feasible,stable and objective.
Keywords:Chaihuang Qingyi Huoxue Granules  orthogonal test  transfer rate  geniposide  extraction process
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