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70岁以上心房颤动患者导管射频消融治疗临床分析
引用本文:薛玉梅,詹贤章,吴书林,杨平珍,廖洪涛,方咸宏,魏薇.70岁以上心房颤动患者导管射频消融治疗临床分析[J].中华老年心脑血管病杂志,2011,13(3):195-198.
作者姓名:薛玉梅  詹贤章  吴书林  杨平珍  廖洪涛  方咸宏  魏薇
作者单位:广东省心血管病研究所广东省人民医院心内科广东省医学科学院,广州,510100
摘    要:目的 分析70岁以上心房如动(房颤)患者导管射频消融治疗成功率及术后复发危险因素.方技,选择导管射频消融的70岁以上房颤患者107例,收集患者临床和电生理资料,采用Cox比例风险回归模型分析房颤消融术后复发危险因素.结果 107例患者中,阵发性房颤89例.持续性房颤18例.平均随访(25.2±11.5)个月,单次消融成...

关 键 词:心房颤动  导管消融术  复发  手术后并发症  肺静脉  预测  危险因素

Catheter ablation treatment in patients older than 70 years of age with atrial fibrillation
Abstract:Objective To evaluate the feasibility and safety of catheter ablation in patients older than 70 years of age with atrial fibrillation(AF),and to identify predictors for recurrent atrial arrhythmias. Methods The clinical outcome of 107 patients with a follow-up>6 months who underwent catheter ablation for paroxysmal and persistent AF(89 and 18 patients respectively) was analyzed.Catheter ablation strategies included:circumferential pulmonary vein ablation(CPVA) and complex ablation.Cox proportional hazard multivariate regression analysis was performed to identify the predictors for recurrent atrial arrhythmias after ablation.Results After mean follow-up for(25.2±11.5) months,72 patients(67.3%) were freed from AF after a single ablation procedure. For the patients with paroxysmal AF and persistent AF,the success rates were 74.2%and 33.3%respectively.For arrhythmia recurrences,7 patients underwent repeated procedures and after which 6 patients remained free from AF.The total success rate was 72.9%.Cox regression analysis indicated that the predictors for recurrence were structural heart disease and AF at the end of the procedure.CPVA decreased the risk of recurrent atrial arrhythmias.There were 4 serious complications including 2 pericardial tamponade,1 hemothorax and 1 death.Conclusions Catheter ablation is an effective treatment for patients over 70 years of age with paroxysmal AF. Structural heart disease and AF at the end of procedure are predictors for recurrent atrial arrhythmias. CPVA may decrease the risk of recurrent atrial arrhythmias,especially in paroxysmal AF.
Keywords:atrial fibrillation  catheter ablation recurrence  postoperative complications  pulmonary veins  forecasting  risk factors
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