Buphthalmos in the setting of persistent hyperplastic primary vitreous cataract

PURPOSE: To report a case of unilateral persistent hyperplastic primary vitreous cataract presenting with ipsilateral buphthalmos. DESIGN: Retrospective case report. METHODS: The patient chart was reviewed, and a relevant literature search was performed. RESULTS: A four-month-old child presented with persistent hyperplastic primary vitreous cataract in the right eye and ipsilateral buphthalmos with no discernable angle abnormalities. He underwent lensectomy, anterior vitrectomy, and limited transscleral diode cyclodestruction in the right eye. CONCLUSIONS: This appears to be the first report of buphthalmos presenting with unilateral persistent hyperplastic primary vitreous. Despite two comorbidities, the patient has thus far responded well to initial treatment and visual rehabilitation.