丝虫特异IgG4试剂盒在流动人口丝虫病监测中的应用

目的了解IgG4试剂盒在消除丝虫病地区流动人口监测中的应用价值。方法应用丝虫特异IgG4试剂盒,检测重点省原丝虫病流行区外来流动人口,同时检测本市居民和6~12岁儿童特异IgG4,阳性者进行病原学检测。结果检测外来流动人口2132例,丝虫特异IgG4阳性5例,阳性率为0.23%,其中安徽省阳性率为0.30%;检测本地居民1094例,丝虫特异IgG4阳性1例,阳性率为0.09%;检测本市儿童1038例,未检出抗体阳性者。IgG4阳性者均进行了病原学检测,未发现微丝蚴血症。结论丝虫特异IgG4试剂盒适用于消除丝虫病地区外来流动人口监测。

Application of filarial-specific IgG4 testing kit in the surveillance of filarial infection in mobile population

Objective To evaluate the filarial-specific IgG4 testing kit for the surveillance of filarial infection in mobile population. Methods The mobile population from some provinces which were heavily endemic areas of filariasis was observed to detect the filarial infection by filarial-specific IgG4 testing kit. Some of local residents and children were detected by the kit too. The filarial-specific IgG4 positives were examined by the parasitological detection method. Results Five out of 2132 mobile people were positive in the test with 0.23% of positive rate, among them, 0.30% of the mobile population who came from Anhui Province were positive. One out of 1094 local residents was positive with 0.09% of positive rate. No positive was found in the local children. No microfilaremia positive was detected in serum by parasitological detection. Conclusion The filariaial-specific IgG4 testing kit is suit to be used in the filariasis surveillance for mobile population.