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| 慢性肝炎肝组织病理改变与血清总胆汁酸关系探讨 | |
| 引用本文： | 张月荣,邱新平,陈世耀. 慢性肝炎肝组织病理改变与血清总胆汁酸关系探讨[J]. 实用肝脏病杂志, 2004, 7(2): 99-100 |
| 作者姓名： | 张月荣 邱新平 陈世耀 |
| 作者单位： | 1. 730050,甘肃省兰州市第一人民医院肝病科 2. 辽宁阜新矿务局总医院消化科 3. 上海复旦大学附属中山医院消化科 |
| 摘 要： | 目的 研究空腹血清总胆汁酸(TBA)与血清纤维化指标的关系，阐明其临床意义。方法 收集慢性肝病患者73例，肝组织活检当天行血清TBA及HA检测，并分析其相关性。结果 慢性肝炎患者TBA水平与正常值相比明显升高，与肝组织炎症活动(G)、纤维化程度(S)及血清纤维化指标(HA)呈正相关，相关系数r分别为0．515、0．430、0．687。结论 TBA是反映肝脏炎性活动及肝纤维化的较敏感指标。 |
| 关 键 词： | 慢性肝炎 肝组织 病理改变 血清总胆汁酸 |
Correlation between serum total bile acid level and hepatic activity index and hepatic fibrosis in patients with chrohic hepatitis |
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| Zhang Yuerong. Correlation between serum total bile acid level and hepatic activity index and hepatic fibrosis in patients with chrohic hepatitis[J]. Journal of Clinical Hepatology, 2004, 7(2): 99-100 | |
| Authors: | Zhang Yuerong |
| Abstract: | Objective To study the correlation between serum total bile acid (TBA) level and the liver injuries.Methods In 73 patients,TBA and HA were detected by automatic biochemistry analyzer and RIA.The liver biopsies were performed.Results The level of serum TBA in patients with chronic hepatitis significantly increased compared with normal control.From G 1 to G 4,and from S 0-1 to S 4,the level of TBA elevated.There was a significantly positive correlation between TBA level and liver inflammation as well as fibrosis.Conclusion TBA is one of the sensitive marker reflecting liver inflammation and fibrosis,which is similar to HA for liver fibrosis markers. |
| Keywords: | Chronsc hepatitis Total bile acid Liver biopsy |
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