| 咪达唑仑和吗啡联合治疗COPD有创通气患者的临床效果观察 |
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| 引用本文： | 杨贺英,朱明,曲海,吴玉娟,张涛,杨亚青.咪达唑仑和吗啡联合治疗COPD有创通气患者的临床效果观察[J].昆明医学院学报,2011,32(11):115-117. |
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| 作者姓名： | 杨贺英 朱明 曲海 吴玉娟 张涛 杨亚青 |
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| 作者单位： | 1. 昆明市延安医院中心ICU 云南昆明 650051
2. 昆明市五华区医院麻醉科,云南昆明,650031 |
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| 摘 要： | 目的机械通气对慢性阻塞性肺病（COPD）有创通气的患者进行镇静镇痛治疗.方法将265例COPD急性加重期有创通气治疗的患者随机分为两组,常规治疗基础上加用咪达唑仑组126例及咪达唑仑联用吗啡组139例,比较两组机械通气的疗效及咪达唑仑的用量.结果机械通气期间联用吗啡组患者与对照组比较,心率、呼吸频率、二氧化碳分压和气道阻力降低,而氧分压则升高,且咪达唑仑用量、平均通气时间、ICU入住时间少于对照组,脱机成功率高于对照组,两组经比较差异有统计学意义（P〈0.05）.结论对COPD有创通气患者进行控制性的镇静、联合镇痛治疗可以获得满意的镇静镇痛及机械通气效果,同时明显减少镇静剂的用量,缩短患者的平均通气时间、ICU入住时间,提高脱机成功率.
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| 关 键 词： | 咪达唑仑 吗啡 慢性阻塞性肺病 有创通气 |
Effects of Midazolam Combined with Morphine in the Treatment of COPD Patients who Received Invasive Ventilation |
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| YANG He-ying,ZHU Ming,QU Hai,WU Yu-juan,ZHANG Tao,YANG Ya-qing.Effects of Midazolam Combined with Morphine in the Treatment of COPD Patients who Received Invasive Ventilation[J].Journal of Kunming Medical College,2011,32(11):115-117. |
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| Authors: | YANG He-ying ZHU Ming QU Hai WU Yu-juan ZHANG Tao YANG Ya-qing |
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| Institution: | YANG He-ying1),ZHU Ming1),QU Hai1),WU Yu-juan1),ZHANG Tao1),YANG Ya-qing2)(1)Dept.of Intensive Care Unit,The Affiliated Yuan'an Hospital of Kunming Medical University,Kunming Yunnan 650051,2)Dept.of Anesthesia,Wuhua Hospital of Kunming,Kunming Yunnan 650031,China) |
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| Abstract: | Objective To give sedation analgesia treatment to chronic obstructive pulmonary disease(COPD)patients with invasive ventilation and observe the efficacy of mechanical ventilation.Methods 265 COPD patients in acute exacerbation who were treated with invasive ventilation were randomly divided into two groups: Conventional therapy plus midazolam group(126 cases)and midazolam combined with morphine group(139 cases).The efficacy of mechanical ventilation and the usage amount of midazolam were compared between tw... |
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| Keywords: | Midazolam Morphine Chronic obstructive pulmonary disease Invasive ventilation |
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