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儿童过敏性紫癜免疫因子研究概况
引用本文:韩广强,;柏树刚.儿童过敏性紫癜免疫因子研究概况[J].实用中医内科杂志,2014(12):170-172.
作者姓名:韩广强  ;柏树刚
作者单位:[1]辽宁中医药大学2012年级消化、肿瘤方向研究生,沈阳110032; [2]辽宁中医药大学附属医院治未病科,沈阳110032
摘    要:过敏性紫癜属"葡萄疫"、"斑毒"等范畴,为六淫之邪侵袭,伤及血络,血不循常道,或摄食异物,素体不受,或药物过敏,致热毒入侵,热伤血络,血溢脉外,渗于肌肤而发斑。从IL-6发病机制、临床观察(西医、中医),VCAM-1发病机制、临床观察(西医、中医)等方面,介绍儿童过敏性紫癜免疫因子研究概况。过敏性紫癜发病机制尚不完全明确,但发病机制与机体免疫功能异常有关,多种免疫因子参与发病,IL-6及VCAM-1参与过敏性紫癜发病过程。过敏性紫癜治疗、预后及肾损害评估仍需大量临床研究,重视中医四诊结合辨证,采取中西医结合治疗手段,提高治愈率及改善预后。

关 键 词:儿童过敏性紫癜  免疫因子  葡萄疫  斑毒  IL-6  VCAM-1  发病机制  综述

The Research Progress of Immune Factors Children Henoch-Schonlein Purpura
Institution:HAN Guangqiang,BAI Shugang(Liaoning University of Traditional Chinese Medicine:a. 2012 graduate of digestive tumors direction, b. Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, department of treating disease, Shenyang 110032,China )
Abstract:The main cause of malignant bowel obstruction is diet without control, air stagnation blood stasis, dampness and heat evil blockade, cold evil in intestine. result in disorders of qi blood yin yang and air blood block in meridian. Appear pathological state of qi stagnation, blood stasis, tanning. Have close relationship with spleen and stomach. The deficiency of spleen cause abnormal movements, this will involve the large intestine and lead to constipation. Spleen can not unifying blood also can lead to bleeding and blood in the stool. deficiency of spleen throughout the entire process of colon cancer. The deficiency of stomach can not use the method of jiangzhuo. Dampness, toxin combined with phlegm and congestion, block intestinal, form the bump, obstruction the running of qi and blood, lead to more deficiency of spleen, this will cause abnormal movements, eventually leading to intestinal obstruction. Chinese medicine treatment including oral, external and clyster, Extensive application of the crowd, especially for frail patients and inoperable, the clinical results were satisfactory and worth to spread.
Keywords:malignant bowel obstruction  constipation  acute disease of tumor  pathogenesis  treatment principles  oral  external  clyster  TCM therapy
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