百令胶囊联合西药治疗糖尿病肾病随机平行对照研究 |
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引用本文: | 宗岚,;丁广存. 百令胶囊联合西药治疗糖尿病肾病随机平行对照研究[J]. 实用中医内科杂志, 2014, 0(12): 57-59 |
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作者姓名: | 宗岚, 丁广存 |
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作者单位: | [1]山东省枣庄市立四院内科; [2]山东省枣庄科技职业学院附院口腔医学专业,山东枣庄277500 |
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摘 要: | [目的]观察百令胶囊联合西药治疗糖尿病肾病疗效。[方法]使用随机平行对照方法,将100例门诊及住院患者按抽签法简单随机分为两组。胰岛素控制血糖,辛伐他汀进行降血脂,同时予饮食指导,低蛋白饮食,控制热量。对照组50例氯沙坦钾,50mg/次,1次/d;复方a-酮酸,3.15g/次,3次/d。治疗组50例百令胶囊,1g/次,3次/d;西药治疗同对照组。连续治疗60d为1疗程。观测临床症状、血肌酐(Scr)、尿素氮(BUN)、血红蛋白(Hb)、白蛋白(Alb)、不良反应。连续治疗6疗程,判定疗效。[结果]治疗组痊愈5例,显效20例,有效19例,无效6例,总有效率88.00%。对照组痊愈1例,显效17例,有效15例,无效17例,总有效率66.00%。治疗组疗效优于对照组(P0.05)。[结论]百令胶囊联合西药治疗糖尿病肾病效果显著,值得推广。
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关 键 词: | 糖尿病肾病 百令胶囊 氯沙坦钾 复方a-酮酸 Scr BUN Hb Alb 随机平行对照研究 |
Bailing Capsule Combined with Western Treatment of Diabetic Nephropathy Randomized Parallel Group Study |
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Affiliation: | ZONG Lan,DING Guangcun(1 Zaozhuang City Shandong Province four Hospital Department; 2 Shandong Zaozhuang Vocational College of Technology Affiliated; Zaozhuang 277500,Shandong,China ) |
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Abstract: | [Objective] To observe the Bailing Capsule Combined with Western Medicine diabetic nephropathy. [Methods]Random parallel control method, 100 outpatients and inpatients by lottery method is simple randomized into two groups. Insulin to control blood sugar, cholesterol-lowering simvastatin, while I dietary guidance, low-protein diet, control the heat. A control group of 50 patients losartan potassium, 50mg/times, 1 times/d. Compound a-keto acid, 3.15g/time, 3 times/d. Treatment group of 50 patients Bailing Capsule, 1g/time, 3 times/d. Western medicine with the control group. 60 d is a continuous course of treatment. Observation of clinical symptoms, serum creatinine(Scr), blood urea nitrogen(BUN), hemoglobin(Hb), albumin(Alb), adverse reactions. 6 courses of continuous treatment to determine efficacy. [Results] The cure five cases, 20 cases markedly effective in 19 cases, six cases, the total efficiency of 88.00%.Cured one case in the control group, 17 cases markedly effective in 15 cases, 17 cases, the total efficiency of 66.00%. Treatment group than the control group( P〈0.05).[Conclusion]Bailing Capsule Combined with Western Medicine diabetic nephropathy effect is remarkable, worthy of promotion. |
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Keywords: | Diabetic nephropathy Bailing Capsule Losartan potassium Compound a-keto acids Scr BUN Hb Alb randomized parallel group study |
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