针刺联合西药治疗类风湿性膝关节炎随机平行对照研究

目的]观察针刺联合西药治疗类风湿性膝关节炎疗效。方法]使用随机平行对照方法,将30例住院患者按病志号抽签法简单随机分为两组。对照组15例乌头汤(乌头、麻黄各15g,甘草6g,白芍10g,黄芪15g;偏重加防风15g,络石藤、青风藤各10g;寒邪偏重加细辛15g,干姜10g;湿邪偏重加防己10g,威灵仙15g,独活10g,羌活15g,木鳖子10g);2剂/d,水煎200m L,早晚口服。治疗组15例西药:美洛昔康,7.5mg/次,2次/d,口服;甲氨蝶呤,7.5mg/次,2次/7d,口服;叶酸,10mg/次,3次/d,口服。针刺:取穴膝眼、足三里、鹤顶,常规消毒,0.40mm×50mm毫针,进针35~40mm,平补平泻法,得气后留针40min,2次/d,连续8d后止。连续治疗30d为1疗程。观测临床症状、晨僵时间、血沉、C反应蛋白、类风湿因子、不良反应。治疗3疗程(90d),判定疗效。结果]治疗组显效8例,有效4例,无效3例,总有效率80.00%。对照组显效2例,有效4例,无效9例,总有效率40.00%。治疗组疗效优于对照组(P0.05)。结论]针刺联合西药治疗类风湿性膝关节炎疗效满意,无副作用,值得推广。

Acupuncture Combined with Western Medicine Treatment of Rheumatoid Arthritis of the Knee Parallel Randomized Controlled Study

Objective]Acupuncture combined with Western medicine treatment of rheumatoid arthritis of the knee efficacy. Methods]Uses random parallel control method, 30 cases of hospitalized patients by disease Zhi No. balloting method is simple and randomized into two groups. 15 cases in the control group Aconitum soup（Wutou,Mahuang each 15 g, Gancao 6g, Baishao 10 g, Huangqi 15g; emphasis added Fangfeng 15 g, Luoshiteng,Qingfengteng each 10g; emphasis added Xixin 15 g, Ganjiang 10g; emphasis added Fangji 10 g, Weilingxian 15 g, Duhuo 10 g, Qianghuo 15 g, Mubiezi 10g）; 2 a / d, decoction 200 m L, sooner or later orally. Western medicine treatment group, 15 cases： meloxicam, 7.5mg / times, 2 times / d, orally; methotrexate, 7.5mg / time, 2 times / 7d, oral; folic acid, 10 mg / time, 3 times / d oral. Acupuncture： routine disinfection, acupoints knee eye, the full three years, crane top, 0.40 mm × 50 mm needle, the needle 35 ~ 40 mm, reinforcing-reducing method, after the gas needle 40 min, 2 times / d, after successive 8d only. 30 d for a course of continuous treatment. Observation of clinical symptoms, erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor, adverse reactions. 3 courses of treatment（90d）, to determine efficacy. Results]Treatment group 8 cases, 4 cases, 3 cases, the total efficiency 80.00%. Group 2 cases markedly effective in 4 cases, 9 cases, the total efficiency 40.00%. Treatment group than in the control group（P〈0.05）. Conclusion] acupuncture combined with western medicine treatment of rheumatoid arthritis of the knee results were satisfactory, no side effects, it is worth promoting.