酸枣仁汤联合耳穴压豆治疗糖尿病失眠症随机平行对照研究

[目的]观察酸枣仁汤联合耳穴压豆治疗糖尿病失眠症疗效。[方法]使用随机平行对照方法,将136例门诊及住院患者按就诊顺序编号简单随机分为两组。对照组66例艾司唑仑1~2mg/次,1次/d,睡前口服。治疗组70例酸枣仁汤(酸枣仁炒20g,川芎、知母各10g,茯神15g,党参、柏子仁、赤芍、白芍各10g。肝郁加郁金、柴胡各10g;瘀血加桃仁、红花各10g;痰多加胆南星、石菖蒲、秫米各10g;焦虑加淮小麦10g,牡蛎15g),1剂/d,水煎150~200m L,午饭及晚饭后温服;耳穴(神门、皮质下、交感、内分泌和阿是穴)消毒后行王不留行籽压法,指导患者按压2~3次/d,按出有酸麻热胀感,以能耐受为度,1~2min/次,隔日更换1次。连续治疗15d为1疗程。观测临床症状、睡眠情况、血液生化指标(空腹血糖、血尿常规、肝肾功能)、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈38例,显效17例,有效10例,无效5例,总有效率92.86%。对照组痊愈22例,显效19例,有效9例,无效15例,总有效率77.27%。治疗组疗效优于对照组(P0.05)。[结论]观察酸枣仁汤联合耳穴压豆治疗糖尿病失眠症疗效显著,无严重不良反应,值得推广。

Zizyphus Jujube Kernel Soup combined Ear Bean Diabetes Insomnia Random Parallel Control Study

[ Objective] To observe the joint ear bean soup of semen ziziphi spinosae（zs） diabetes insomnia curative effect.[ Methods] Using random parallel control method, 136 cases of outpatient and inpatient medical order numbering method simply divided into two groups. The control group, 66 cases of estazolam 1 ~ 2 mg/times, 1 / d, oral before sleep. Treatment group, 70 cases of zizyphus jujube kernel soup, Fried zizyphus jujube kernel 20 g, rhizoma ligustici wallichii, rhizoma anemarrhenae, 10 g each, 15 g to god eight, dangshen, platycladi seed, radix paeoniae rubra, radix paeoniae alba every 10 g; liver depression and radix curcumae, radix bupleuri, 10 g; blood stasis and peach kernel, safflower every 10 g; phlegm more bravery south star, stone calamus, husked sorghum every 10 g; anxiety and huai wheat 10 g, oysters, 15 g）, 1 / d, water frying, 150~200 m L, warm clothing; after lunch and dinner; Ear（god door, subcortical, sympathetic, endocrine and hole） initiated cowherb seed seed disinfection method, to guide the patients for 2 ~ 3 times/d, according to the acid hemp thermal feeling, with pain not for degree, 1 ~ 2 min/times, replaced every day. 15 d continuous treatment for 1 course of treatment. Observation of clinical symptoms, improve sleep, blood biochemical indicators（fasting blood glucose, blood in urine routine, liver and kidney function）, adverse reactions. Continuous treatment 2 period of treatment, judge curative effect.[ Result] The treatment group 38 cases cured, 17 cases had marked effect, 10 cases were effective, invalid in 5 cases, total effective rate was 92.86%. Control group recover 22 cases, 19 cases were markedly improved, effective 9 cases, 15 cases were invalid, the total effective rate was 77.27%. The treatment group curative effect is better than that of control group（P〈 0.05）.[ Conclusion] Joint ear bean soup of semen ziziphi spinosae（zs） diabetes insomnia with obvious therapeutic effect, is worth promoting.