Hamster endogenous retrovirus (HaER) isolated from SV-40 induced tumor cells |
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| Authors: | Anna Goldschmied-Reouven A. Yaniv K. Perk |
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| Affiliation: | 1. Department of Human Microbiology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
2. Department of Animal Science, Hebrew University Faculty of Agriculture, Rehovoth, Israel
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| Abstract: | A hamster cell line obtained from a secondary transplanted SV-40-induced tumor was found to spontaneously release type C virus particles. The particles possessed all biochemical features characteristic of retroviruses and induced syncytium formation in XC cells but were not oncogenic for hamsters. Nucleic acid hybridization assays demonstrated that the isolated virus was an endogenous retrovirus of hamster, lacking sequence homology with mouse and other animal species. |
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