超重、运动、吸烟、饮酒与西藏人群胆囊结石患病风险的横断面调查研究

目的研究超重、运动、吸烟、饮酒与西藏拉萨地区行政干部人群胆囊结石患病风险的关系。方法对2006年1月至2010年5月在武警西藏总队医院体检的全区行政干部4000人进行了横断面问卷调查和分析体检结果。其中女1678人,年龄(42.3±13.1)岁;男2322人,年龄(42.5±12.9)岁。结果胆囊结石的患病率男、女性分别为11.0%和22.3%。体重指数≥25.0kg/m2,每日饮酒量>20g和每周运动时间<2h是胆囊结石的危险因素(P<0.05)。在有胆囊结石的人群中脂肪肝的患病率为46.4%,无胆囊结石人群中脂肪肝的患病率为29.8%,χ2=43.529,P<0.01。结论这一随机选择的人群脂肪肝、胆道疾病、肥胖的患病率很高,饮酒、脂肪肝、缺乏运动可以认为是这一人群患胆囊结石的危险因素。

Overweight,physical activity,tobacco and alcohol consumption in a cross-sectional random sample of adults of Tibeten China with gallstone disease

Objective To investigate the correlation and significance of overweight,physical activity,tobacco and alcohol consumption in a cross-sectional random sample of adults of Tibeten China with gallstone disease.Methods Participating in the present study were 4000 adults（1678 females 42.0%];2322 males 58.0%],age：20-65 years）randomly chosen from an administrative population undergone physical examination in our hospital in Lhasa,Tibet of China.Data were obtained by means of a questionnaire,analysis of anthropometric data.Results The prevalence of gallstone disease reportedly ranges from approximately 11.0% in men to 22.3% in women.A high body mass index（BMI≥25.0 kg/m2）,alcohol consumption in grams per day（20 grams）,hours of exercise per week（2 hours/week）were identified as risk factors in men while in females.The only risk factors were increasing age and a high BMI.The incidence of fatty liver in the groups with gallstone disease is 46.4% and is 29.8% in the groups without gallstone disease（χ2 =43.529,P0.01）.Conclusions This random sample of an administrative population in Lhasa,Tibet of China was characterised by a high prevalence of fatty liver,biliary disease and obesity.This and the pattern of alcohol consumption and physical activity can be considered to put this group at high risk for associated gallstone disease.