远视儿童应用1%环戊通与1%阿托品检影验光的比较

目的比较3~7岁远视儿童先后应用1%环戊通与1%阿托品散瞳检影验光的屈光度值。方法对我院眼科门诊3~7岁儿童,先用1%环戊通滴眼液点眼3次后检影验光;对一眼远视屈光度值≥+0.75D者,再采用1%阿托品眼膏点眼3d后检影验光。共50例(90眼)纳入本研究,年龄(5.3±1.4)岁。屈光度按等效球镜值计算,应用配对t检验和2χ检验对数据进行统计学处理。结果①应用1%环戊通和1%阿托品验光的屈光度值分别为(+3.67±2.39)D和(+4.52±2.49)D,P0.001;②伴有内斜视组应用1%环戊通和1%阿托品验光的屈光度值分别为(+3.95±2.30)D和(+4.91±2.51)D,P0.001,两者屈光度差值为(+0.97±0.75)D;不伴内斜视组应用1%环戊通和1%阿托品验光的屈光度值分别为(+3.32±2.49)D和(+4.03±2.41)D,P0.001,两者屈光度差值为(+0.70±0.40)D;③在应用两种药物验光的屈光度差值≤0.75D的55眼和0.75D的35眼中,应用1%环戊通初始验光的屈光度≥+3D和+3D眼数的差异无统计学意义(P=0.562)。结论对于3~7岁远视儿童尤其是伴有内斜视者,应首选使用1%阿托品散瞳验光。

Comparative study of cyclopentolate 1% and atropine 1% in retinoscopic refraction for Chinese hyperopic children

Objective To compare cycloplegic retinoscopic refractions using cyclopentolate 1% and atropine 1% in Chinese hyperopic children of 3 to 7 years old. Methods Cyclopentolate 1% was used for cycloplegic retinoscopy on 3 to 7 years old children from outpatient clinic, and 1 week later, atropine 1% was used for cycloplegic retinoscopy on children who had a cycloplegic refraction larger than +0.75D. 50 children (90 eyes) were enrolled in this study. Refraction was presented as spherical equivalent (SE), and paired sample t test and χ2 test were used to analyze the data. Results （1）The SE of retinoscopy for cyclopentolate 1% and atropine 1% was +3.67±2.39D and +4.52±2.49D, respectively（P＜0.001）; （2）in esotropic children, the SE of retinoscopy for cyclopentolate 1% and atropine 1% was +3.95±2.30D and +4.91±2.51D, respectively（P＜0.001）; in children without esotropia, the SE of retinoscopy for cyclopentolate 1% and atropine 1% was +3.32±2.49D and +4.03±2.41D, respectively（P＜0.001）; the SE difference between cyclopentolate 1% and atropine 1% in esotropic and non esotropic children was +0.97±0.75D and +0.70±0.40D, respectively（P＜0.001）;（3）in 55 eyes with SE difference ≤0.75D and 35 eyes with SE difference ＞0.75D, the number of eyes with cyclopentolate 1% SE ≥+3D and ＜+3D had no statistical difference (P=0.562). Conclusion In 3 to 7 years old Chinese hyperopic children, especially esotropic children, atropine 1% is the choice of drug in cycloplegic retinoscopy.