血糖与脑卒中意识障碍及近期预后的关系

本研究纳入146例急性脑卒中患者,测定其发病早期血糖值,同时对其意识状况进行GCS评分,并观察其近期预后。结果提示早期血糖水平与GCS呈明显负相关关系,高血糖组昏迷发生率和病死率均明显高于非高血糖组,近期预后差,昏迷组及死亡组血糖均值和高血糖发生率均明显高于非昏迷组及存活组。治疗上推荐使用胰岛素,而且应尽量避免引起血糖增高的因素,使血糖维持在正常水平,以期能改善息者的近期预后和减少神经功能缺损。

A study of relationship between early blood glucose level and unconsciousness of early prognosis in acute stroke.

In this study. 146 non -diabetic patients with acute stroke were divided into 3 sets of controlled groups: hyperglycemia and normoglycemia, coma and non-coma, and death and survival. Fasting blood glucose assay and Glasgow Coma Scale (GCS) scoring were carried out within 24 - 72 hours after the onset, and the early prognosis was evaluated. The results revealed that early blood glucose level had minus correlation with GCS scores, the hyperglycemia group had higher coma occurrence rate, higher mortality rate and poorer early prognosis than the normoglycemia group. The coma group and the death group had higher mean blood glucose level and higher hyperglycemia occurrence rate than the non - coma group and the survival group. Administration of insulin with combination of potassium chloride and avoidance of hyperglycemia-causing factors were recommended in the treatment of acute stroke for the sake of improving the early prognosis and reducing the neurological deficit.