1996-2001年住院复治肺结核患者结核分枝杆菌耐药性的调查

目的 探讨住院复治肺结核患者的耐药情况.方法 对1996-2001年培养阳性的1385例住院肺结核患者中440例复治肺结核患者的耐药情况按年龄分组进行回顾性分析.结果 总耐药率以青年组最高.耐2药及以上者比例较耐1药比例高,青年组耐R率明显高于老年组;耐2药中,以耐HR占首位.总的耐多药率为49.5%,青年组高达73.9%.结论 复治肺结核患者的高耐药率应引起足够重视,需采取更多措施降低耐药率.

The investigation on drug resistance of hospitalized previously retreated tuberculosis patients during 1996-2001 in our hospital

Objective To investigate the situation of drug resistance of hospitalized previously treated pulmonary tuberculosis patients. Method To analyze and compare the drug resistance of 440 cases of retreated pulmonary tuberculosis from 1385 baterilogical positive pulmonary tuberculosis cases during 1996 - 2001. Results The total rate of drug resistance in youth group was the highest. The proportion of 2 and above drugs resistance was higher than that of 1 drugresistance. The rate of R resistance in youth group was obviously higher than that in old age group. The rate of HR resistance was the highest in 2 drug resistance group. The total rate of multi - drug resistance was 49.5% ,but that in youth group was as high as 73.9%. Conclusion We should pay more attention to the grave situation of drug resistance of the patients with retreated pulmonasy tuberculosis. It is important to take the more measures to reduce the rate of drug resistance.