胚胎发育不良性神经上皮瘤的MRI与病理学对照

目的探讨胚胎发育不良性神经上皮瘤（DNT）的MRI表现及病理特征。方法对11例经手术病理证实的胚胎发育不良性神经上皮瘤MRI资料进行回顾性分析，并与低级别星形细胞瘤、少枝胶质细胞瘤、神经节细胞胶质瘤、蛛网膜囊肿等进行鉴别，重点研究DNT的发生部位、形态特征、MRI信号特点、强化方式等情况。结果11例患者的病灶均局限于皮层或以皮层为主，呈长T1长1、2信号，FLAIR及DWI像呈等低信号；病灶以额顶叶最多见；7例病灶形态呈典型的“三角征”；11例患者肿瘤内均见到多发囊变区及等信号分隔；9例瘤周无水肿，无占位效应；增强扫描2例有强化。结论大部分DNT其MRI表现具有特征性，表现为皮层内三角形长T1长舵信号，内有等信号分隔，无占位效应，多数不强化。当病变缺乏特征性表现时，诊断较为困难；特殊胶质一神经原成分是DNT的组织病理学特征。

Comparison of MRI and Pathological Diagnosis of Dysembryoplastic Neuroepithelial Tumor(a report of 11 cases)

Objective To evaluate MRI features and pathology character of dysembryoplastic neuroepithelial tumor （DNT）. Methods MRI features and pathology character in 11 cases of DNT confirmed by histopathology were studied retrospectively, and discriminated strictly from low level astrocytoma, oligodendroglioma, ganglioglioma, arachnoid cyst, etc. The emphasis was played on location of DNT,pathological changes,modality,trait of MRI signal,intensify manner etc. Results The focus of all 15 patients were located in the cerebral cortex or mostly in the cerebral cortex. The lesions were of high intensity on T1 and of high intensity on T2, the imagine of FLAIR and DWI was low signal. Localization of lesions was predominantly in the frontal and parie- tal lobes. Modality of 7 cases lesion was typical triangle sign. The lesions of 11 cases showed multiple cystic changes, and equal signal compartmentation. 9 cases devoided of peritumoral edema or mass effect. The lesions had contrast enhancement in 2 cases. Conclusion Mostly MRI features of DNT is of characteristics showing typical triangle sign in cortex and high intensity on T1 and of high intensity on T2 and equal signal compartmentation, no mass effect and no contrast enhancement generally. The diagnosis for lesions lacking of typical representation was difficult. Specific giioneuronal neurons were typical manifestation of DNT in patho- logical examination.